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Initially, 3D printing was used for prototyping, but now this method is being used to create functional final products. – Three-dimensional (3D) printing is a rapidly expanding manufacturing method.
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Therefore, higher quality 3D printers and more detailed investigation into the MakerBot MakerWare printing settings are recommended if consistent material properties or geometries are required. – Although desktop 3D printers are an attractive manufacturing option to quickly produce functional components, this study suggests that users must be aware of this manufacturing process’ inherent limitations, especially for components requiring high geometric tolerance or specific material properties. Dimensional analysis of test specimens shows that the test specimen varied significantly (p < 0.05) from the nominal print dimensions. – DOE results suggest that per cent infill has a significant effect on the longitudinal elastic modulus and ultimate strength of the test specimens, whereas print orientation and layer thickness fail to achieve significance.
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Dimensional accuracy of test samples was also investigated. Classical laminate plate theory was used to compare results from the DOE experiments with theoretically predicted elastic moduli for the tensile samples. – A design of experiments (DOE) test protocol was applied to determine the effect of the following variables on the material properties of 3D printed part: layer height, per cent infill and print orientation using a MakerBot Replicator. – This paper aims to evaluate the material properties and dimensional accuracy of a MakerBot Replicator 2 desktop 3D printer. A time-lapse video of the stage during operation and as part of a custom assembled screening robot can be found at. We describe positioning characteristics of the stage, including spatial resolution, accuracy and repeatability, compare imaging data generated with our device to data obtained using a commercially available microplate reader, demonstrate its suitability to high-content microscopy in 96-well high-throughput screening format and validate its applicability to automated functional Cl- and Ca2+-imaging with recombinant HEK293 cells as a model system. The fully assembled device is light-weight (1.1 kg), small (33×20×8 cm) and extremely low-cost (approx. System assembly including 3D printing requires approx.
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Here we describe a 3D printed inexpensive open source and scalable motorized positioning stage for automated high-content screening microscopy and provide detailed step-by-step instructions to re-building the device, including a comprehensive parts list, 3D design files in STEP (Standard for the Exchange of Product model data) and STL (Standard Tessellation Language) format, electronic circuits and wiring diagrams as well as software code. The increasing availability of rapid prototyping technology makes it possible to quickly engineer alternatives to conventional automation infrastructure that are low-cost and user-friendly. High-content screening microscopy relies on automation infrastructure that is typically proprietary, non-customizable, costly and requires a high level of skill to use and maintain. The drilling operation is performed by the combination of the movements of the drilling system and the base on which workpiece is kept for drill operations.In this paper innovative design and efficient programming have been merge to generate a device which will significantly contribute to the field of production. Finally the prototype model is developed in order to facilitate drilling operation with ease and accuracy.
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Then the actuation and control part is taken care with the help of actuating elements like DC motor, mechanical wheels and by programming it effectively using PLC. System setup is crafted using PRO-E software based on the design considerations. So for this purpose, initially the design of the drilling In this paper, stress is laid on the designing of an automated drilling system so to perform drilling operation automatically in efficient way.
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An automated device which replaces manual involvement is an extraordinary contribution to the mankind. Involvement of automation in manufacturing technology plays an important role in enhancing the quality of process and products.
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